Therapeutic effect of pH responsive Magainin II modified azithromycin plus curcumin micelles in different depth models of MRSA infection

Therapeutic effect of pH responsive Magainin II modified azithromycin plus curcumin micelles in different depth models of MRSA infection

Abstract Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen responsible for serious infections in humans. The overuse of antibiotics has led to the evolution of resistance genes in bacteria. This study aimed to develop a pH-responsive micelle, loaded with therapy drugs and modifi...

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Bibliographic Details
Main Authors: Lu Zhang, Rui-bo Guo, Yang Liu, Liang Kong, Juan Zang, Zi-xu Zhang, Jia-hua Wang, Mu-han Chen, Mo Liu, Yang Yu, Xue-tao Li
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
MRSA
Curcumin
Active targeting
Polymer micelle
Environmental response
Online Access:https://doi.org/10.1038/s41598-025-92384-z
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https://doi.org/10.1038/s41598-025-92384-z

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