Hirudin-Based Treatment of Diabetes-Induced Erectile Dysfunction Through Inhibition of the HIF-1α to Regulate RhoA/ROCK Signaling Pathway: An In Vivo Animal Experiment

Hirudin-Based Treatment of Diabetes-Induced Erectile Dysfunction Through Inhibition of the HIF-1α to Regulate RhoA/ROCK Signaling Pathway: An In Vivo Animal Experiment

Diabetes-induced erectile dysfunction (DIED) is a type of refractory erectile dysfunction which can be clinically treated using the traditional Chinese medicine leech whose main ingredient is hirudin. Oxidative stress can damage vascular endothelial cells, affect blood circulation, and induce fibros...

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Main Authors: Longji Sun, Nianwen Huang, Chao Yang, Junlong Feng, Hui Chen, Weidong Feng, Zixiang Gao, Bin Wang, Jisheng Wang
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:American Journal of Men's Health
Online Access:https://doi.org/10.1177/15579883241310763
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https://doi.org/10.1177/15579883241310763

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