Utility of Germline, Somatic and ctDNA Testing in Adults With Cancer

Utility of Germline, Somatic and ctDNA Testing in Adults With Cancer

ABSTRACT Background and Aim Historical genetic sequencing of specific cancer variants has been superseded by comprehensive genomic profiling (CGP). This narrative review aimed to capture current international evidence on the clinical utility of CGP for cancer prevention, detection and treatment. Mat...

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Main Authors: Emily DeBortoli, Ella McGahan, Tatiane Yanes, Jennifer Berkman, Lauren G. Aoude, Amelia K. Smit, Akira Gokoolparsadh, Azure Hermes, Lyndsay Newett, Mackenzie Bourke, Susan Hanson, Helen Hughes, Oliver Hofmann, Ilias Goranitis, Rebekah McWhirter, Vivienne Milch, Julia Steinberg, Aideen McInerney‐Leo
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Cancer Medicine
Subjects:
cancer
ctDNA
genetics
genomics
germline
narrative review
Online Access:https://doi.org/10.1002/cam4.71080
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https://doi.org/10.1002/cam4.71080

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