Taurine ameliorates cellular senescence associated with an increased hydrogen sulfide and a decreased hepatokine, IGFBP-1, in CCl4-induced hepatotoxicity in mice

Taurine ameliorates cellular senescence associated with an increased hydrogen sulfide and a decreased hepatokine, IGFBP-1, in CCl4-induced hepatotoxicity in mice

This study investigated the protective effects of taurine against cellular senescence and hepatokine secretion in a mouse model of carbon tetrachloride (CCl4)-induced chronic liver injury. Oral taurine administration by tap water containing 3 % taurine significantly attenuated liver damage, as evide...

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Bibliographic Details
Main Authors: Akihiro Tsuboi, Hamida Khanom, Riki Kawabata, Takanori Matsui, Shigeru Murakami, Takashi Ito
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
Subjects:
Taurine
Senescence
Hepatokines
Hydrogen sulfide
Liver injury
IGFBP-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001533
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