Synergistic Effects of <i>Pyrrosia lingua</i> Caffeoylquinic Acid Compounds with Levofloxacin Against Uropathogenic <i>Escherichia coli</i>: Insights from Molecular Dynamics Simulations, Antibiofilm, and Antimicrobial Assessments

Synergistic Effects of <i>Pyrrosia lingua</i> Caffeoylquinic Acid Compounds with Levofloxacin Against Uropathogenic <i>Escherichia coli</i>: Insights from Molecular Dynamics Simulations, Antibiofilm, and Antimicrobial Assessments

Urinary tract infections (UTIs), primarily caused by uropathogenic <i>Escherichia coli</i> (UPEC), have high morbidity and recurrence rates. Resistance to levofloxacin hydrochloride (LEV), a commonly used treatment for UTIs, is increasingly problematic, exacerbated by biofilm formation m...

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Bibliographic Details
Main Authors: Yan Zhang, Fangfang Jiao, Derong Zeng, Xiang Yu, Yongqiang Zhou, Juan Xue, Wude Yang, Jingjing Guo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
UTIs
UPEC
<i>Pyrrosia lingua</i>
levofloxacin
molecular simulation
Online Access:https://www.mdpi.com/1420-3049/29/23/5679
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