CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.

CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.

Candida is the most common human fungal pathogen and causes systemic infections that require neutrophils for effective host defense. Humans deficient in the C-type lectin pathway adaptor protein CARD9 develop spontaneous fungal disease that targets the central nervous system (CNS). However, how CARD...

Full description

Saved in:
Bibliographic Details
Main Authors: Rebecca A Drummond, Amanda L Collar, Muthulekha Swamydas, Carlos A Rodriguez, Jean K Lim, Laura M Mendez, Danielle L Fink, Amy P Hsu, Bing Zhai, Hatice Karauzum, Constantinos M Mikelis, Stacey R Rose, Elise M N Ferre, Lynne Yockey, Kimberly Lemberg, Hye Sun Kuehn, Sergio D Rosenzweig, Xin Lin, Prashant Chittiboina, Sandip K Datta, Thomas H Belhorn, Eric T Weimer, Michelle L Hernandez, Tobias M Hohl, Douglas B Kuhns, Michail S Lionakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005293
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1371/journal.ppat.1005293

Similar Items