Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Abstract It is widely believed that Silybum marianum (Silymarin) alleviates liver injury arising from various etiologies with different degrees of damage through its anti-inflammatory and antioxidant activities. This meta-analysis investigated the effects of silymarin administration on serum levels...

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Main Authors: Kasra Shahsavari, Shireen Shams Ardekani, Mohammad Reza Shams Ardekani, Majid Mokaber Esfahani, Hossein Kazemizadeh, Tannaz Jamialahmadi, Mehrdad Iranshahi, Mahnaz Khanavi, Maede Hasanpour
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Silybum marianum
Silymarin
Liver injury
Hepatoprotective effects
Clinical trials
Meta-analysis
Online Access:https://doi.org/10.1186/s12906-025-04886-y
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https://doi.org/10.1186/s12906-025-04886-y

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