Transcriptomic HEPN1 signatures predict treatment response in low grade glioma

Abstract Background Iron-dependent ferroptosis emerges as a promising therapeutic avenue for glioma treatment, with ferroptosis-related genes such as HEPN1 offering potential as critical biomarkers when analyzed at single-cell resolution. By leveraging comprehensive single-cell transcriptomic approa...

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Bibliographic Details
Main Authors: Lei Jiao, Shuhua Fang, Jianbo Zhang
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-03395-1
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