Toxoplasma gondii modulates immune responses and mitigates type 1 diabetes progression in a streptozotocin-induced rat model

Abstract Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. Emerging evidence suggests that infections, including Toxoplasma gondii (T. gondii), may modulate immune responses and influence disease outcomes. This stu...

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Main Authors: Kimia Moradi, Reyhaneh Moghaddami, Arshad Ghaffari-Nasab, Monir Khordadmehr, Abdol Sattar Pagheh, Hossein Mosajakhah, Sahar Rezaei, Esmaeil Gharepapagh, Mahdi Ahmadi, Mahbobeh Montazeri, Hossein Pazoki, Ehsan Ahmadpour
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-025-02168-1
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