Evaluation of the optimal timing of radiotherapy in EGFR-Mutant oligometastatic NSCLC through a retrospective analysis of treatment sequences and survival outcomes

Evaluation of the optimal timing of radiotherapy in EGFR-Mutant oligometastatic NSCLC through a retrospective analysis of treatment sequences and survival outcomes

Abstract Non-small cell lung cancer (NSCLC) with EGFR mutations presents a unique challenge due to the development of oligometastasis during treatment with first-line tyrosine kinase inhibitors (TKIs). The optimal timing of radiotherapy in EGFR-mutant oligometastatic NSCLC remains debated. This stud...

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Bibliographic Details
Main Authors: Meng Zhang, Lan Wang, Qi Wang, Tian-Hui Guo, Wen Gao, Bi-Yuan Zhang, Hai-Ji Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
EGFR-mutant NSCLC
Oligometastatic disease
Radiotherapy
Tyrosine kinase inhibitors (TKIs)
Online Access:https://doi.org/10.1038/s41598-025-15056-y
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https://doi.org/10.1038/s41598-025-15056-y

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