T-cell receptor dynamics in digestive system cancers: a multi-layer machine learning approach for tumor diagnosis and staging

BackgroundT-cell receptor (TCR) repertoires provide insights into tumor immunology, yet their variations across digestive system cancers are not well understood. Characterizing TCR differences between colorectal cancer (CRC) and gastric cancer (GC), as well as developing machine learning models to d...

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Bibliographic Details
Main Authors: Changjin Yuan, Bin Wang, Hong Wang, Fang Wang, Xiangze Li, Ya’nan Zhen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1556165/full
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