Effect of immune infiltration intensity on the efficacy of neoadjuvant immunotherapy for esophageal cancer

BackgroundEsophageal squamous cell carcinoma (ESCC) treatment often involves neoadjuvant therapy combining chemotherapy and immune checkpoint inhibitors. However, the effectiveness of these treatments is limited by immune infiltration in the tumor microenvironment.MethodsWe analyzed single-cell tran...

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Bibliographic Details
Main Authors: Yong Zhang, Xinyao Xu, Xiaorong Mu, Juzheng Wang, Jipeng Zhang, Guangyu Xiang, Jiahe Li, Chunlong Zheng, Huaiyu Wang, Qiang Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1543283/full
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