Single‐Cell RNA Sequencing Reveals the Critical Role of SEC16B in Lung Metastasis of Osteosarcoma

Single‐Cell RNA Sequencing Reveals the Critical Role of SEC16B in Lung Metastasis of Osteosarcoma

ABSTRACT Osteosarcoma (OS) is highly malignant and easily prone to lung metastasis. The mechanisms of lung metastasis in OS remain unclear. The single‐cell RNA sequencing (scRNA‐seq) samples in this study included six primary osteosarcoma samples (published in‐house data), two lung metastasis sample...

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Main Authors: Shangyu Liu, Haijun Tang, Shanhang Li, Jian Guan, Yangjie Cai, Hening Li, Weijie Yan, Wei Dai, Danting Xiao, Zhuan Zou, Wenyu Feng, Xinli Zhan, Yun Liu, Juliang He
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:FASEB BioAdvances
Subjects:
lung metastasis
osteosarcoma
single‐cell transcriptomics
tumor microenvironment
Online Access:https://doi.org/10.1096/fba.2024-00161
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https://doi.org/10.1096/fba.2024-00161

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