Interaction of brequinar and analogs with PD-L1: a molecular docking analysis
Aim: The immunosuppressive drug brequinar (BQR) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) active against autoimmune diseases and viral infections. This oral drug is currently evaluated for the treatment of cancers, notably acute myeloid leukemia to limit the suppressive function...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Open Exploration
2025-06-01
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| Series: | Exploration of Drug Science |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/uploads/Article/A1008113/1008113.pdf |
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