Chemotherapy treatment alters DNA methylation patterns in the prefrontal cortex of female rat brain

Abstract Chemotherapy can cause several long-term side effects that can affect cancer survivors’ quality of life-, notably cognitive decline in response to select chemotherapeutic agents. Studies using both human patients and animal models have been employed to determine the regions of the brain tha...

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Bibliographic Details
Main Authors: Shami Chakrabarti, Chanchal Wagh, Ciara Bagnall-Moreau, Fathema Uddin, Joshua Reiser, Kaliris Salas-Ramirez, Tim Ahles, Karen Hubbard
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-07419-2
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