Microbial metabolites control self-renewal and precancerous progression of human cervical stem cells

Microbial metabolites control self-renewal and precancerous progression of human cervical stem cells

Abstract Cervical cancer is the fourth most common female cancer, with the uterine ectocervix being the most commonly affected site. However, cervical stem cells, their differentiation, and their regulation remain poorly understood. Here, we report the isolation of a population enriched for human ce...

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Main Authors: Jihyeon Myeong, Minho Lee, Bawool Lee, Joon Hyung Kim, Yeji Nam, Yeseul Choi, Jeongmin Kim, Se Young Jeon, Haewon Shim, Da-Ryung Jung, Youngjin Shin, Minsoo Jeong, Byungmoo Oh, Jaehun Jung, Christine S. Kim, Hyung Soo Han, Jae-Ho Shin, Yoon Hee Lee, Nora Jee-Young Park, Gun Oh Chong, Youngtae Jeong
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57323-6
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https://doi.org/10.1038/s41467-025-57323-6

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