The decision‐making process and criteria in selecting candidate drugs for progeria clinical trials

Abstract Hutchinson–Gilford progeria syndrome (progeria) is an extremely rare premature aging disease with a population prevalence of 1 in 20 million. Nevertheless, propelled by the discovery of a causal mutation in the lamin A/C gene (LMNA) (De Sandre‐Giovannoli et al, 2003; Eriksson et al, 2003) a...

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Bibliographic Details
Main Authors: Leslie B Gordon, Mark W Kieran, Monica E Kleinman, Tom Misteli
Format: Article
Language:English
Published: Springer Nature 2016-05-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201606280
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