Employing Multi-Omics Analyses to Understand Changes during Kidney Development in Perinatal Interleukin-6 Animal Model

Employing Multi-Omics Analyses to Understand Changes during Kidney Development in Perinatal Interleukin-6 Animal Model

Chronic kidney disease (CKD) is a leading cause of morbidity and mortality globally. Maternal obesity during pregnancy is linked to systemic inflammation and elevated levels of the pro-inflammatory cytokine interleukin-6 (IL-6). In our previous work, we demonstrated that increased maternal IL-6 duri...

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Bibliographic Details
Main Authors: Ganesh Panzade, Tarak Srivastava, Daniel P. Heruth, Mohammad H. Rezaiekhaligh, Jianping Zhou, Zhen Lyu, Mukut Sharma, Trupti Joshi
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Cells
Subjects:
chronic kidney disease (CKD)
interleukin-6 (IL-6)
multi-omics
miRNA regulation
epigenetics
co-expression
Online Access:https://www.mdpi.com/2073-4409/13/19/1667
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