Ventromedial hypothalamic nucleus neuronal nitric oxide knockdown effects on GABAergic neuron metabolic sensor and transmitter marker gene expression in the male rat

Ventromedial hypothalamic nucleus neuronal nitric oxide knockdown effects on GABAergic neuron metabolic sensor and transmitter marker gene expression in the male rat

Abstract The diffusible gas nitric oxide (NO) and amino acid γ-gamma-aminobutyric acid (GABA) exert contrary effects on glucose counterregulation in the male rat, but how these neurochemical signals integrate within ventromedial hypothalamic nucleus (VMN) neural circuitries remains unclear. Female r...

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Bibliographic Details
Main Authors: Sagor C. Roy, Madhu Babu Pasula, Subash Sapkota, Karen P. Briski
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Neuroscience
Subjects:
nNOS siRNA
GABA neuron
GAD1/2
Glucokinase
AMPK
Glucagon
Online Access:https://doi.org/10.1186/s12868-025-00940-0
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https://doi.org/10.1186/s12868-025-00940-0

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