Effects of latent infection of Toxoplasma gondii strains with different genotypes on mouse behavior and brain transcripts

Effects of latent infection of Toxoplasma gondii strains with different genotypes on mouse behavior and brain transcripts

Abstract Background Toxoplasma gondii can cause severe damage to immunodeficient hosts, and also compromise brain structure and function in immunocompetent hosts during latent infection. In China, the two different isolates, Chinese I (ToxoDB#9) and Chinese III are dominant epidemic strains widely s...

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Main Authors: Bei-Bei Zhou, Hong-Jie Dong, Hang Sun, Xiao-Man Xie, Huan-Huan Xie, Wen-Ju Zhu, Ya-Nan Li, Chao Xu, Jian-Ping Cao, Gui-Hua Zhao, Kun Yin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
Cerebral cysts
Differentially expressed transcripts
Nanopore RNA-seq
Mental and behavioral disorders
Online Access:https://doi.org/10.1186/s13071-025-06819-7
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https://doi.org/10.1186/s13071-025-06819-7

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