In-depth insight into structure-reactivity/regioselectivity relationship of Lewis acid catalyzed cascade 4πe-cyclization/dicycloexpansion reaction

Abstract The Lewis acid-catalyzed tittle reaction of 1,3-dicycloalkenlidine ketones is recognized as so far the shortest and most effective 1-step method for construction of angular tricyclic scaffolds, which are extensively found in bioactive terpenoids. Here, a further kinetic study of this reacti...

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Bibliographic Details
Main Authors: Ka Lu, Pan-Pan Zhou, Yong-Qiang Tu, Fu-Min Zhang, Xiao-Ming Zhang, Kai Li, Kun Fang, Yun-Peng Wang, Zi-Hao Li, Jia-Qi Li
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57859-7
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