Comparison of ERlangen Score with pTau/Aβ1-42 Ratio for Predicting Cognitive Decline and Conversion to Alzheimer’s Disease

Comparison of ERlangen Score with pTau/Aβ1-42 Ratio for Predicting Cognitive Decline and Conversion to Alzheimer’s Disease

<b>Background/Objectives</b>: The ERlangen Score (ERS) and the pTau/Aβ1-42 ratio are dementia risk scores that use only surrogate markers of amyloid and tau pathology, whose performance has taken on added importance with the advent of anti-amyloid antibody therapies. Direct comparisons b...

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Bibliographic Details
Main Authors: Julian Alexander Schwarz, Pauline Schulz, Janine Utz, Laura Rudtke, Johannes Jablonowski, Neele Klement, Piotr Lewczuk, Johannes Kornhuber, Juan Manuel Maler, Timo Jan Oberstein
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Brain Sciences
Subjects:
ERlangen Score
risk of dementia
area under the curve
pTau/Aß1-42
comparison
cognitive decline
Online Access:https://www.mdpi.com/2076-3425/15/4/334
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