Treatment with intravenous immunoglobulin modulates coagulation- and complement-related pathways in COVID-19 patients

Treatment with intravenous immunoglobulin modulates coagulation- and complement-related pathways in COVID-19 patients

IntroductionIntravenous immunoglobulin (IVIG) is a therapy that uses pooled immunoglobulins from thousands of different donors. While it is primarily used to treat immunodeficiency and autoimmune diseases due to its immunomodulatory properties, IVIG has also been used as an off-label therapy for res...

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Main Authors: Dominic McGrosso, Jessica Raygoza, Avnee J. Kumar, Michael T. Y. Lam, Laura A. Barnes, Sophia Karandashova, Alexia Perryman, Matthew Geriak, Mazen F. Odish, Nicole G. Coufal, Brian Lichtenstein, George Sakoulas, Angela Meier, Victor Nizet, Jorge A. Masso-Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
COVID-19
ARDS
intravenous immunoglobulin
IVIg
mass spectrometry
tandem mass tag
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623309/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623309/full

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