Role of Nitric Oxide, Nitric Oxide Synthase, Soluble Guanylyl Cyclase, and cGMP-Dependent Protein Kinase I in Mouse Stem Cell Cardiac Development

Introduction and Aim. Nitric oxide (NO) can trigger cardiac differentiation of embryonic stem cells (ESCs), indicating a cardiogenic function of the NO synthetizing enzyme(s) (NOS). However, the involvement of the NO/NOS downstream effectors soluble guanylyl cyclase (sGC) and cGMP activated protein...

Full description

Saved in:
Bibliographic Details
Main Authors: Valentina Spinelli, Alessia Vona, Francesca Corti, Lorenzo Diolaiuti, Matteo Zanardelli, Laura Sartiani, Paola Failli
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2016/2868323
Tags: Add Tag
No Tags, Be the first to tag this record!