Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

Fast, scalable generation of high‐quality protein multiple sequence alignments using Clustal Omega

Abstract Multiple sequence alignments are fundamental to many sequence analysis methods. Most alignments are computed using the progressive alignment heuristic. These methods are starting to become a bottleneck in some analysis pipelines when faced with data sets of the size of many thousands of seq...

Full description

Saved in:
Bibliographic Details
Main Authors: Fabian Sievers, Andreas Wilm, David Dineen, Toby J Gibson, Kevin Karplus, Weizhong Li, Rodrigo Lopez, Hamish McWilliam, Michael Remmert, Johannes Söding, Julie D Thompson, Desmond G Higgins
Format: Article
Language:English
Published: Springer Nature 2011-10-01
Series:Molecular Systems Biology
Subjects:
bioinformatics
hidden Markov models
multiple sequence alignment
Online Access:https://doi.org/10.1038/msb.2011.75
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/msb.2011.75

Similar Items