Immunogenicity of RSV Fusion Protein Adsorbed to Non-Pathogenic <i>Bacillus subtilis</i> Spores: Implications for Mucosal Vaccine Delivery in Nonclinical Animal Models

Immunogenicity of RSV Fusion Protein Adsorbed to Non-Pathogenic <i>Bacillus subtilis</i> Spores: Implications for Mucosal Vaccine Delivery in Nonclinical Animal Models

<b>Background/Objectives</b>: Mucosal vaccines are rare but commercially desirable because of their real and theoretical biological advantages. Spores and vegetative forms from Bacillus have been used as probiotics due to their stability under various environmental conditions, including...

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Bibliographic Details
Main Authors: Jianying Xiao, Hao Wang, Cheryl Callahan, Gregory O’Donnell, Silveria Rodriguez, Ryan P. Staupe, Carl J. Balibar, Michael P. Citron
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
Subjects:
mucosal vaccines
intranasal vaccines
adjuvants
<i>Bacillus subtilis</i> spores
mice
cotton rats
Online Access:https://www.mdpi.com/2227-9059/13/5/1112
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