Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling

Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling

Curcumin, a major phytochemical derived from Curcuma longa, has been shown to enhance the efficacy of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and cisplatin by overcoming drug resistance, making it a promising adjunct in the treatment of glioblastoma. However, the global gene-exp...

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Bibliographic Details
Main Authors: Nicole Tendayi Mashozhera, Chinreddy Subramanyam Reddy, Yevin Nenuka Ranasinghe, Purushothaman Natarajan, Umesh K. Reddy, Gerald Hankins
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
glioblastoma-U87 cells
natural compound
curcumin
apoptosis
RNA-seq
Online Access:https://www.mdpi.com/1420-3049/30/10/2108
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