Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction

Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction

Objective Obesity-associated metabolic dysfunction increases the risk of multiple diseases such as type 2 diabetes and cardiovascular disease. The importance of the co-stimulatory CD40-CD40L dyad in diet-induced obesity (DIO), with opposing phenotypes arising when either the receptor (aggravating) o...

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Bibliographic Details
Main Authors: Lisa Willemsen, Myrthe den Toom, Myrthe E Reiche, Marion J J Gijbels, Esther Lutgens, Bram van Os, Norbert Gerdes, Suzanne A B M Aarts
Format: Article
Language:English
Published: BMJ Publishing Group 2019-05-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/7/1/e000829.full
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https://drc.bmj.com/content/7/1/e000829.full

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