Stable topical application of antimicrobials using plumbing rings in an ex vivo porcine corneal infection model.

Microbial keratitis (MK) is a substantial cause of clinical blindness worldwide. Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium and is the leading cause of MK. Infection models are vital tools in understanding host-pathogen interactions and the development of novel therapies. As...

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Bibliographic Details
Main Authors: Daniel M Foulkes, Keri Mclean, Tarunima Sharma, David G Fernig, Stephen B Kaye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0319911
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