Palmitoylation: an emerging therapeutic target bridging physiology and disease

Abstract Palmitoylation is a reversible post-translational lipid modification of proteins, catalyzed by the Zinc finger DHHC domain-containing (ZDHHC) family of palmitoyltransferases. Palmitoylation plays a pivotal role in regulating localization, stability, trafficking, and interactions, thereby co...

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Bibliographic Details
Main Authors: Weini Li, Jie Shen, Aojia Zhuang, Ruiheng Wang, Quanqi Li, Anas Rabata, Yanan Zhang, DuoYao Cao
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-025-00776-w
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