Combining diffusion and transformer models for enhanced promoter synthesis and strength prediction in deep learning

Combining diffusion and transformer models for enhanced promoter synthesis and strength prediction in deep learning

ABSTRACT In the field of synthetic biology, the engineering of synthetic promoters that outperform their natural counterparts is of paramount importance, which can optimize the expression of exogenous genes, enhance the efficiency of metabolic pathways, and possess substantial commercial value. Rese...

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Bibliographic Details
Main Authors: Xin Lei, Xing Wang, Guanlin Chen, Ce Liang, Quhuan Li, Huaiguang Jiang, Wei Xiong
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mSystems
Subjects:
deep learning
diffusion model
synthetic promoter
transformer
Online Access:https://journals.asm.org/doi/10.1128/msystems.00183-25
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https://journals.asm.org/doi/10.1128/msystems.00183-25

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