Nicotinamide Mononucleotide and Nicotinamide Riboside Improve Dyslipidemia and Fatty Liver but Promote Atherosclerosis in Apolipoprotein E Knockout Mice

Nicotinamide Mononucleotide and Nicotinamide Riboside Improve Dyslipidemia and Fatty Liver but Promote Atherosclerosis in Apolipoprotein E Knockout Mice

<b>Background:</b> Nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) are intermediary products in NAD+ metabolism. NMN and NR supplementation can elevate NAD+ levels in tissues, addressing health issues associated with aging and obesity. However, the impact of NMN and NR o...

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Bibliographic Details
Main Authors: Pin Wang, Jia-Xin Li, Yuan-Yuan Kong, Si-Li Zheng, Chao-Yu Miao
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
nicotinamide mononucleotide
nicotinamide riboside
ApoE knockout mice
fatty liver
atherosclerosis
Online Access:https://www.mdpi.com/1424-8247/18/3/281
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