Robust circulating microRNA signature for the diagnosis and early detection of pancreatobiliary cancer

Robust circulating microRNA signature for the diagnosis and early detection of pancreatobiliary cancer

Abstract Background A new circulating biomarker superior to carbohydrate antigen 19–9 (CA19-9) is needed for diagnosing pancreatobiliary cancer (PBca). The aim of this study was to identify serum microRNA (miRNA) signatures comprising reproducible and disease-related miRNAs. Methods This multicenter...

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Main Authors: Shuichi Mitsunaga, Masafumi Ikeda, Makoto Ueno, Satoshi Kobayashi, Masahiro Tsuda, Ikuya Miki, Takamichi Kuwahara, Kazuo Hara, Yukiko Takayama, Yutaro Matsunaga, Keiji Hanada, Akinori Shimizu, Hitoshi Yoshida, Tomohiro Nomoto, Kenji Takahashi, Hidetaka Iwamoto, Hideaki Iwama, Etsuro Hatano, Kohei Nakata, Masafumi Nakamura, Hiroko Sudo, Satoko Takizawa, Atsushi Ochiai
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medicine
Subjects:
Pancreatobiliary cancer
Circulating microRNA
Biomarker
Online Access:https://doi.org/10.1186/s12916-025-03849-x
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https://doi.org/10.1186/s12916-025-03849-x

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