Distinctive grade based on Ki67 index and immune microenvironment of metastatic pancreatic neuroendocrine tumors responding to capecitabine plus temozolomide

Distinctive grade based on Ki67 index and immune microenvironment of metastatic pancreatic neuroendocrine tumors responding to capecitabine plus temozolomide

Abstract Background Ki67 index changes during the treatment of metastatic pancreatic neuroendocrine tumor (PanNET) treatment. The study aimed to detect alterations of grade based on Ki67 index and immune microenvironment in PanNET responding to capecitabine/temozolomide (CapTem). Method Retrospectiv...

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Main Authors: Heli Gao, Wuhu Zhang, Zheng Li, Wensheng Liu, Mengqi Liu, Qifeng Zhuo, Yihua Shi, Wenyan Xu, Chenjie Zhou, Yi Qin, Jin Xu, Jie Chen, Xianjun Yu, Xiaowu Xu, Shunrong Ji
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Pancreatic neuroendocrine tumor
Ki67 index
Capecitabine/temozolomide
Upgrading
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12885-024-13117-5
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https://doi.org/10.1186/s12885-024-13117-5

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