PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

PD-1/PD-L1 Axis Downregulation in Guillain-Barré Syndrome: A Potential Mechanism Driving the Autoimmune Pathogenesis

Introduction: Guillain-Barré syndrome (GBS), an immune-mediated disorder of the peripheral nervous system characterized by progressive muscle weakness, is often triggered by Campylobacter jejuni infection. Molecular mimicry between C. jejuni's lipo-oligosaccharides (LOS) and host nerve ganglios...

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Main Authors: Mr Rasel Ahmed, Mrs Israt Jahan, Mrs Pritha Biswash, Miss Mehjabeen Haque, Miss Sarah Khurshid, Mr Jigishu Ahmed, Mr Sayed Akib Hossain, Dr Zhahirul Islam
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224004880
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