Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital
Objective: To study immediate therapeutic outcomes, subsequent fertility effects and menstrual changes in cesarean scar pregnancy patients who received uterine artery embolization with or without methotrexate followed by ultrasound guided curettage. Materials and methods: Totally, 82 patients who me...
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Elsevier
2025-01-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455924002821 |
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| author | Ying Feng Huiqiao Gao Fang Liu Shuzhen Wang Meizhu Xiao |
| author_facet | Ying Feng Huiqiao Gao Fang Liu Shuzhen Wang Meizhu Xiao |
| author_sort | Ying Feng |
| collection | DOAJ |
| description | Objective: To study immediate therapeutic outcomes, subsequent fertility effects and menstrual changes in cesarean scar pregnancy patients who received uterine artery embolization with or without methotrexate followed by ultrasound guided curettage. Materials and methods: Totally, 82 patients who met the inclusion criteria were enrolled in our study and divided into two groups. Group I included 50 patients who received uterine artery embolization and ultrasound guided curettage, and Group II had 32 patients who received uterine artery embolization plus methotrexate and ultrasound guided curettage. Results: No significant difference was found in demographic features between the two groups, but the level of serum β-human chorionic gonadotropin before uterine artery embolization, 1 day and 7 days after ultrasound guided curettage is significantly higher in Group II than that in Group I. Patients were followed up for a mean time of 38.9 months. 10 patients had reproductive desire and half of them failed while half succeeded including one recurrent cesarean scar pregnancy. Most patients (74.4 %) had no menstrual changes, while 19 patients complaint a decrease in menstruation and 2 patients had a prolonged menstruation. Conclusion: Uterine artery embolization combined with or without methotrexate plus ultrasound guided curettage is an effective, safe and recommended therapy to eliminate the gestational sac and meanwhile to preserve fertility for cesarean scar pregnancy patients, and methotrexate could help reduce the blood level of β-human chorionic gonadotropin and shorten the days to recover to normal, thus reducing hospitalized days. |
| format | Article |
| id | doaj-art-079a900ba54b473191e04bf1947e25cd |
| institution | Kabale University |
| issn | 1028-4559 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj-art-079a900ba54b473191e04bf1947e25cd2025-01-09T06:12:51ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592025-01-016418691Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospitalYing Feng0Huiqiao Gao1Fang Liu2Shuzhen Wang3Meizhu Xiao4Department of Ultrasound, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong'an Road, Xi-cheng District, Beijing, ChinaDepartment of Gynecology & Obstetrics, Beijing Chao-yang Hospital, Capital Medical University, No. 8, Gongti South Road, Chao-yang District, Beijing, ChinaDepartment of Pathology, Shanghai East Hospital Ji'an Hospital, No. 80, Ji'an Nan da Dao, Ji'zhou Distinct, Ji'an, Jiangxi Province, ChinaDepartment of Gynecology & Obstetrics, Beijing Chao-yang Hospital, Capital Medical University, No. 8, Gongti South Road, Chao-yang District, Beijing, ChinaDepartment of Gynecology & Obstetrics, Beijing friendship hospital, Capital Medical University, No. 95, Yong’an Road, Xi-cheng district, Beijing, China; Corresponding author.Objective: To study immediate therapeutic outcomes, subsequent fertility effects and menstrual changes in cesarean scar pregnancy patients who received uterine artery embolization with or without methotrexate followed by ultrasound guided curettage. Materials and methods: Totally, 82 patients who met the inclusion criteria were enrolled in our study and divided into two groups. Group I included 50 patients who received uterine artery embolization and ultrasound guided curettage, and Group II had 32 patients who received uterine artery embolization plus methotrexate and ultrasound guided curettage. Results: No significant difference was found in demographic features between the two groups, but the level of serum β-human chorionic gonadotropin before uterine artery embolization, 1 day and 7 days after ultrasound guided curettage is significantly higher in Group II than that in Group I. Patients were followed up for a mean time of 38.9 months. 10 patients had reproductive desire and half of them failed while half succeeded including one recurrent cesarean scar pregnancy. Most patients (74.4 %) had no menstrual changes, while 19 patients complaint a decrease in menstruation and 2 patients had a prolonged menstruation. Conclusion: Uterine artery embolization combined with or without methotrexate plus ultrasound guided curettage is an effective, safe and recommended therapy to eliminate the gestational sac and meanwhile to preserve fertility for cesarean scar pregnancy patients, and methotrexate could help reduce the blood level of β-human chorionic gonadotropin and shorten the days to recover to normal, thus reducing hospitalized days.http://www.sciencedirect.com/science/article/pii/S1028455924002821Cesarean scar pregnancyFertilityMethotrexateUterine artery embolizationUltrasound guided curettage |
| spellingShingle | Ying Feng Huiqiao Gao Fang Liu Shuzhen Wang Meizhu Xiao Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital Taiwanese Journal of Obstetrics & Gynecology Cesarean scar pregnancy Fertility Methotrexate Uterine artery embolization Ultrasound guided curettage |
| title | Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital |
| title_full | Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital |
| title_fullStr | Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital |
| title_full_unstemmed | Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital |
| title_short | Uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy: Five-year experience at a single tertiary hospital |
| title_sort | uterine artery embolization plus ultrasound guided curettage for cesarean scar pregnancy five year experience at a single tertiary hospital |
| topic | Cesarean scar pregnancy Fertility Methotrexate Uterine artery embolization Ultrasound guided curettage |
| url | http://www.sciencedirect.com/science/article/pii/S1028455924002821 |
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