Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1

Vitexicarpin suppresses colorectal and non-small cell lung cancer via selective inhibition of Anoctamin 1

Colorectal cancer (CRC) and non-small cell lung cancer (NSCLC) remain among the most challenging malignancies to treat due to therapy complexity, adverse events, and dose-limiting toxicities, which often result in treatment failure. NSCLC, in particular, has a high mortality rate attributed to late-...

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Main Authors: Yohan Seo, Sion Lee, Raju Das, Sung Baek Jeong, Chul Soon Park, Minuk Kim, Deok Kyu Yoon, Armin Sultana, Kantu Das, Jae-Eon Lee, Yong Hyun Jeon, Phan Thi Thanh Huong, Nguyen Xuan Nhiem, Joohan Woo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
ANO1
vitexicarpin
colorectal cancer
non-small cell lung cancer
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1557193/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1557193/full

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