Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on Pancreatic PaCa-2 and Melanoma A375 Cancer Cells

Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on Pancreatic PaCa-2 and Melanoma A375 Cancer Cells

Synthetic compounds are widely used in cancer drug discovery. Chemotherapies aim to inhibit proliferation and induce apoptosis however, they have limitations. This study aims to explore in vitro anti-proliferative, pro-apoptotic, and anti-metastatic effects of 2-imino-7-methoxy-4-(4-fluorophenyl)-2...

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Bibliographic Details
Main Authors: Mpho Ndou, Marthe C. D. Fotsing, Michael H. K. Kengne, Edwin M. Mmutlane, Derek T. Ndinteh, Mthokozisi B.C. Simelane, Lesetja Motadi, Mpho Choene
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-01-01
Series:Acta Medica Iranica
Subjects:
Cancer
Synthetic compounds
PaCa-2
A375
Anti-proliferation
Pro-apoptosis
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/10951
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