Interaction Between Apolipoprotein L1 Genetic Risk and Neighborhood Socioeconomic Status for Kidney Outcomes in a United States Cohort

Interaction Between Apolipoprotein L1 Genetic Risk and Neighborhood Socioeconomic Status for Kidney Outcomes in a United States Cohort

Introduction: Apolipoprotein L1 (APOL1) risk alleles G1 and G2, confer a higher risk of kidney outcomes but are influenced by other genetic and environmental factors. The interaction between neighborhood socioeconomic status (SES) and APOL1 associated risk of kidney outcomes is unknown. Methods: Thi...

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Bibliographic Details
Main Authors: Kullaya Takkavatakarn, Dinushika Mohottige, Alexander W. Charney, Carol Horowitz, Andrew G. Rundle, Lili Chan, Girish N. Nadkarni
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Kidney International Reports
Subjects:
APOL1
gene-environment interaction
kidney outcome
median household income
neighborhood socioeconomic status
poverty rate
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925001044
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