Sodium oleate functionalized simvastatin liposomes: boosting endosomal escape and anticancer efficacy in triple negative breast cancer

Sodium oleate functionalized simvastatin liposomes: boosting endosomal escape and anticancer efficacy in triple negative breast cancer

Background and purpose: Due to delivery obstacles, Simvastatin, a potential anticancer agent, faces clinical limitations. This study aimed to enhance simvastatin delivery and efficacy against triple-negative breast cancer (TNBC) by developing liposomes modified with sodium oleate (NaOL) to improve e...

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Bibliographic Details
Main Authors: Ebrahim Sadaqa, Satrialdi, Fransiska Kurniawan, Diky Mudhakir
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Research in Pharmaceutical Sciences
Subjects:
endosomal escape
liposomes
simvastatin
sodium oleate
triple negative breast cancer
Online Access:https://journals.lww.com/10.4103/RPS.RPS_25_24
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https://journals.lww.com/10.4103/RPS.RPS_25_24

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