RKIP regulates bone marrow macrophage differentiation to mediate osteoclastogenesis and H-type vessel formation

RKIP regulates bone marrow macrophage differentiation to mediate osteoclastogenesis and H-type vessel formation

Abstract As central cells involved in osteoimmunology, bone niche macrophages possess diverse functions, and their differentiation fate regulates bone homeostasis. Elucidation of the underlying mechanism involved in macrophage differentiation is important for developing new therapeutic targets for o...

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Main Authors: Zeyu Zheng, Siyue Tao, Jiayan Jin, Yansong Li, Liya Dai, Zhaobo Huang, Yihao Zhao, Bao Huang, Saijilafu, Wenlong Lin, Xiaojian Wang, Mengrui Wu, Jian Chen, Fengdong Zhao
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62972-8
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https://doi.org/10.1038/s41467-025-62972-8

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