Myeloid‐Derived Suppressor Cell Accumulation Drives Intestinal Fibrosis through mCCL6/hCCL15 Chemokine‐Mediated Fibroblast Activation

Myeloid‐Derived Suppressor Cell Accumulation Drives Intestinal Fibrosis through mCCL6/hCCL15 Chemokine‐Mediated Fibroblast Activation

Abstract Intestinal fibrosis, a severe complication of Crohn's disease (CD), is linked to chronic inflammation, but the precise mechanism by which immune‐driven intestinal inflammation leads to fibrosis development is not fully understood. This study investigates the role of myeloid‐derived sup...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaohui Cheng, Pingwen Shao, XinTong Wang, Juan Jiang, Jiahui Chen, Jie Zhu, Weiming Zhu, Yi Li, Junfeng Zhang, Jiangning Chen, Zhen Huang
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
IBD
intestinal fibroblasts
intestinal fibrosis
mCCL6/hCCL15
MDSCs
Online Access:https://doi.org/10.1002/advs.202411711
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/advs.202411711

Similar Items