Balaglitazone reverses P-glycoprotein-mediated multidrug resistance via upregulation of PTEN in a PPARγ-dependent manner in leukemia cells

Multidrug resistance in tumor cells is still a big challenge in cancer treatment. Therefore, identification ofsafe and effective multidrug resistance–reversing compounds with minimal side effects is an important approach in cancer treatment. Here, we investigated the role and potential mechanisms of...

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Bibliographic Details
Main Authors: Bahman Yousefi, Ako Azimi, Maryam Majidinia, Vahid Shafiei-Irannejad, Reza Badalzadeh, Behzad Baradaran, Nosratollah Zarghami, Nasser Samadi
Format: Article
Language:English
Published: SAGE Publishing 2017-09-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317716501
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