Novel sponge formulation of mesenchymal stem cell secretome and hyaluronic acid: a safe and effective topical therapy for Psoriasis vulgaris

Novel sponge formulation of mesenchymal stem cell secretome and hyaluronic acid: a safe and effective topical therapy for Psoriasis vulgaris

Abstract Background Psoriasis vulgaris is the most common form of psoriasis, yet current treatments often lead to significant side effects, resulting in a high rate of therapy desertion. Here, we explored a novel therapeutic approach using the secretome from Wharton Jelly-derived mesenchymal stem ce...

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Main Authors: Estefanía Elgueta, Catalina P. Prieto, Dan Hartmann, Daniela Carrillo, Natalie Edwards, Constanza Martínez, Dan Pérez, Bárbara Casas, Luis Vergara, Fernando Valenzuela, Verónica Catalán, José Lattus, Felipe Oyarzun-Ampuero, Verónica Palma
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cell
Secretome
Exosomes, hyaluronic acid, Psoriasis vulgaris
MSC-based therapy, cutometer
Online Access:https://doi.org/10.1186/s13287-025-04415-1
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https://doi.org/10.1186/s13287-025-04415-1

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