Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy.

Doxorubicin is a potent chemotherapeutic agent that is widely-used to treat a variety of cancers but causes acute and chronic cardiac injury, severely limiting its use. Clinically, the acute side effects of doxorubicin are mostly manageable, whereas the delayed consequences can lead to life-threaten...

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Bibliographic Details
Main Authors: Izabela Piotrowska, Mark Isalan, Michal Mielcarek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0180571&type=printable
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