Real-world evidence of the effectiveness and utilization of subcutaneous C1INH long-term prophylaxis in patients with HAE in Spain and Germany

Real-world evidence of the effectiveness and utilization of subcutaneous C1INH long-term prophylaxis in patients with HAE in Spain and Germany

Hereditary angioedema (HAE) types 1/2 are rare genetic disorders leading to C1 inhibitor (C1INH) deficiency/dysfunction. Guidelines recommend long-term prophylaxis (LTP) to prevent HAE attacks. Subcutaneous (SC) C1INH replacement therapy is approved for LTP in patients with HAE (age indication varie...

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Bibliographic Details
Main Authors: Marcus Maurer, Stefan Cimbollek, Maebh Kelly, Kyle Rodney, John Elliott, Eduardo LoboGuerrero, Markus Magerl
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
hereditary angioedema
prophylaxis
C1INH
real-world evidence
long-term
subcutaneous
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1576235/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1576235/full

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