Phages ZC01 and ZC03 require type-IV pilus for Pseudomonas aeruginosa infection and have a potential for therapeutic applications

Phages ZC01 and ZC03 require type-IV pilus for Pseudomonas aeruginosa infection and have a potential for therapeutic applications

ABSTRACT There has been a growing interest in bacteriophages as therapeutic agents to treat multidrug-resistant bacterial infections. The present work aimed at expanding the microbiological and molecular characterization of lytic phages ZC01 and ZC03 and investigating their efficacy in the control o...

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Main Authors: Layla Farage Martins, Ariosvaldo Pereira dos Santos Junior, Gianlucca Gonçalves Nicastro, Gaby Scheunemann, Claudia Blanes Angeli, Fernando Pacheco Nobre Rossi, Ronaldo Bento Quaggio, Giuseppe Palmisano, Germán Gustavo Sgro, Kelly Ishida, Regina Lúcia Baldini, Aline Maria da Silva
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas aeruginosa
PA14
phage therapy
phage receptor
type-4 pilus
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01527-24
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https://journals.asm.org/doi/10.1128/spectrum.01527-24

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