Research progress on nanotoxicity and detoxification of cobalt in metal-based implants

Background Cobalt nanoparticles (CoNPs), a primary wear debris from joint prostheses, exhibit significant cytotoxicity. This review aims to synthesize current understanding of CoNPs’ toxicity mechanisms, their local and systemic pathological effects, the emerging role in ferroptosis, potential detox...

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Bibliographic Details
Main Authors: Wentao Fan, Mingxin Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2025.2532120
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