Precision targeting of rhabdomyosarcoma by combining primary CAR NK cells and radiotherapy

Precision targeting of rhabdomyosarcoma by combining primary CAR NK cells and radiotherapy

Background: Rhabdomyosarcoma (RMS) is the most common type of soft-tissue sarcoma in children, and it remains a challenging cancer with poor outcomes in high-risk and metastatic patients. This study reports the use of epidermal growth factor receptor (EGFR)-targeted chimeric antigen receptor (CAR) n...

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Main Authors: Franz Rödel, Elise Gradhand, Winfried S Wels, Martin Michaelis, Lisa Marie Reindl, Lida Jalili, Tobias Bexte, Sabine Harenkamp, Sophia Thul, Stephanie Hehlgans, Alina Wallenwein, Florian Rothweiler, Jindrich Cinatl, Halvard Bonig, Meike Vogler, Evelyn Ullrich
Format: Article
Language:English
Published: BMJ Publishing Group 2025-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/7/e011330.full
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https://jitc.bmj.com/content/13/7/e011330.full

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