A promising approach to diabetic osteoporosis: oxymatrine’s effects on gut microbiota and osteoblasts

Abstract Objectives Oxymatrine (OMT), a quinolizidine alkaloid derived from Sophora flavescens Ait., has demonstrated therapeutic potential in type 2 diabetes mellitus (T2DM). This study aimed to investigate its effects on diabetic osteoporosis (DOP) and explore the underlying mechanisms involving g...

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Bibliographic Details
Main Authors: Yang Zhang, Yiwen Zhu, Mengying Li, Minjie Zhang, Dan Shou, Peijian Tong
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-025-00374-x
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